TRANSCRIPTOMIC ANALYSIS OF HUMAN RETINAL DETACHMENT REVEALS BOTH INFLAMMATORY RESPONSE AND PHOTORECEPTOR DEATH.

Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death.

BackgroundRetinal detachment often leads to a severe and permanent loss of vision and its therapeutic management remains to this day exclusively surgical.We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment in order to identify new potential pharmacological targets tha

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